This is a crucial step in improving the safety and security of biological research in the U.S. Dangerous gain-of-function research has lacked adequate enforcement and transparency for decades, potentially endangering lives through accidental releases or deliberate misuse. The pandemic reaffirmed the catastrophic consequences of insufficient oversight, particularly in facilities with questionable safety standards.
This broad restriction on gain-of-function research threatens to cripple vital scientific progress and pandemic preparedness. Even when proper safeguards exist, the order's sweeping definition could halt important research. Rather than enhancing security, it weakens America's ability to detect, understand, and combat emerging viral threats and damages international scientific collaboration.